Bar Plot from Scientific Research

Ages of onset for TR disease, with the majority of loci having possible pediatric onset. Triangles indicate congenital conditions occurring at birth. Loci are colored by the number of independent observations, defined as unrelated cases/pedigrees as documented in OMIM, GeneReviews, and research literature. Lighter bars connect maximum and minimum reported ages, while opaque lines indicate typical intervals for age of onset, where greater than ten independent observations are available. Loci with less than two independent observations were removed, as was POLG (see the Construction and content section)

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