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Gene expression ratio of CLCN2 in the embryonic skin, the brain, and a body part compared to the wild-type for three genotypes. The CLCN2 expression is significantly downregulated in the Motley embryonic skin sample, compared to the heterozygous and the wild-type, based on a Welch’s t -test. The three asterisks denote a p -value < 0.001 and “ns” a p- value > 0.05. The error bars correspond to the standard deviations
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