Single variant associations, labeled as chromosome:position:reference allele:effect allele (gene) (effect direction), and gene-level associations, labeled as gene (effect direction), with outcomes and risk factors. Only associations with p < 0.05 are shown. For most measurements and all outcomes and risk factors, associations represent a meta-analysis of results from UK Biobank, All of Us , and Bio Me . The color of each box indicates the effect size and direction ( Z score); for display purposes, Z scores are capped at 10 and - 10. Complete data are available in Additional file 1: Tables S9–S10. Abbreviations: CRP, C-reactive protein; ALP alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyltransferase; SHBG, sex hormone binding globulin
