Kaplan-Meier estimates of freedom from the primary endpoint, which is freedom from documented AF more than 30 s after a single procedure, with or without the use of antiarrhythmic medications after the 3-month blanking period. Comparisons of the tailored arm versus the anatomical arm were performed using the two-sided log-rank test. Patients with persistent AF with a duration of AF greater or equal to 6 months in the PP population (HR, 0.18; 95% CI, 0.08–0.40). P < 0.0001 for all comparisons between the tailored and anatomical arms.