Scatter Plot from Scientific Research

Volcano plot of log-transformed P values and fold change (calculated as log 2 of the HR) for all XWAS associations for mortality in the final pooled analysis. Each point represents the effect and P value for the association between a single exposure and all-cause mortality from a Cox proportional hazard model in the XWAS discovery analysis ( n = 218,446). Exposures that were FDR significant in both the discovery and replication stages are colored, whereas associations that were not replicated are indicated in dark gray and grouped in the category *nonreplicated. The top 20 points according to P value are labeled.

DOI