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Schematic of infection (created with BioRender). CD-1 mice were infected with a 1:1 mixture of the indicated strains and the corresponding avc1Δ mutant by intravenous inoculation. Animals were euthanized 4 days post infection, organs were harvested, and colony-forming units for parental and avc1Δ mutants were determined by selective plating as described in STAR Methods.

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