Microscopy from Scientific Research

Immunostaining demonstrates an inhibitory effect of Shh signaling (10 nM) on the apical expression of Aqp1 (top) and Atp1a2 (bottom) in WT choroid plexus explants, which was blunted by Smo inhibition using KAAD. Apical Aqp1 expression (n= 6), DMSO vs. Shh,*p= 0.001; Shh vs. Shh + KAAD,****p< 0.0001. Apical Atp1a2 expression (n= 3), DMSO vs. Shh,*p= 0.0497; Shh vs. Shh + KAAD,*p= 0.0257.

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