Bubble Plot from Scientific Research

Expression levels of ten most significant genes among genes overlapping a GWAS locus (left) or not (right). Genes are ordered by strength of evidence (ppermutation) with decreasing significance from left to right; expression levels of tissue-specific marker genes are shown for reference on the right. Human embryonal gonads. Single-cell average gene expression (color panel) and proportion of cells with non-zero expression (dot size) at different stages of germ cell differentiation (primordial germ cell [PGC], pre-spermatogonia, and pre-oocyte cell types) as well as in male germ cells and supporting cells (Sertoli and fetal Leydig).

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