Microscopy from Scientific Research

cKO sections are also shown from rostral to caudal. cKO brains appear smaller and exhibit several morphological abnormalities. The CA3 hippocampal layer exhibits dysmorphology with abnormal bending and dispersion (black triple arrow in J'). Data are representative of seven cKO and three WT sectioned brains from 11 litters, respectively. CTX, cerebral cortex: STR, striatum; TH, thalamus; HY, hypothalamus; PAL, pallidum; CC, corpus callosum; HC, hippocampal commissure; MB, midbrain; DG, dentate gyrus; CA1, CA2, and CA3 subfields.

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