Schematic representation of the possible mechanism by which phytosphingosine targets PPAR. PA palmitic acid, OA oleic acid, Phy phytosphingosine. Differences among groups were analyzed by one-way ANOVA with Tukey’s post hoc test. *, p < 0.05, **, p < 0.01, and ***, p < 0.001, respectively. The data in the bar plot are presented as the means SD.