Protein Structure from Scientific Research
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Superposition of PTCH1–Tl23 complex (PDB: 7K65) with PTCH1*–Fab 6H3 complex (left) and apo PTCH1 (right, PDB: 6MG8). The conformational changes of PTCH1-ECD1-α5 and rotation of PTCH1-ECD2 triggered by Tl23 compared to apo PTCH1 are indicated.
#Protein Structure#PTCH1#Tl23 Complex#Fab 6H3 Complex#Apo PTCH1#PDB 7K65#PDB 6MG8#Conformational Changes#ECD1#ECD2
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