The anaesthetic-induced loss of ICC is significantly more pronounced for functional connections within the transmodal cortex than those involving unimodal regions. For edges within the transmodal cortex, mean = 0.44 and s.d. = 0.34; for other edges, mean = 0.22 and s.d. = 0.35; t (39,998) = 55.93; P < 0.001; effect size (Hedge’s g ) = 0.63; CI = [0.60, 0.65]; two-sided t -test). The ICC ranges between -1 and +1. n = 5,580 edges within the transmodal cortex and n = 34,420 unimodal–transmodal and unimodal–unimodal edges. In the box plot, the central lines indicate median values, the bounds of the boxes indicate the 25th and 75th percentiles and the whiskers indicate 1.5× the interquartile range.
