Comparison of the default SAM with our fine-tuned model. The bar plot shows the mean segmentation accuracy for interactive segmentation, starting from a single annotation, either a single positive point (green) or a box (red). We then iteratively add a pair of point annotations, one positive, one negative, derived from prediction errors to simulate interactive annotation. The lines indicate the performance for automated instance segmentation methodsAMG (yellow), AIS (dark green) and CellPose (red)using a CellPose model trained on LIVECell. Evaluation is performed on the test set defined in the LIVECell publication 25.
