Network from Scientific Research

Multilevel cell neighborhoods can be computed to analyze and communicate the structure and function of FTUs; tissue image with cell type annotations and zoom into H&E with FTU segmentations (red outlines) and zoom into the multiplexed image (CODEX) is shown in left, neighborhoods are given in the middle; hierarchy of FTUs, neighborhoods, communities and cell types are shown on the right. Datasets are on GitHub 81. ICC, Interstitial cells of Cajal; TA, transit-amplifying; NK, natural killer; DC, dendritic cell; IEL, intraepithelial lymphocytes.

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