Microscopy from Scientific Research

Visualization of signature genes in selected FOVs of the CosMx data. Yellow and green dots represent the signature genes used to calculate the TH and CTX scores, respectively. Cell boundaries are depicted with gray lines; astrocytes are outlined in white. CosMx data include one biological replicate each for WT and AD samples (Supplementary Fig. 2d ); scale bar, 100 m.

DOI