Transcriptomic spots from the Visium data. Spots are color coded according to their constituent astrocytes’ subclusters annotated in a . The opacity of the spots is representative of cell density. Spots not containing astrocytes were removed for clarity. Black boxes represent the corresponding FOVs of the CosMx data (FOV1: AD CTX; FOV6: AD HPF; FOV8: AD TH; FOV4: AD STR; FOV10: WT CTX; FOV14: WT HPF; FOV19: WT TH; FOV17: WT STR); scale bar, 500 m; FC, fold change.
