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Splenic T cells from Sham mice ( n =4) were co-cultured with or without PCs purified from CLP animals ( n =10) at 1:1 ratio for 72 h with anti-PD-L1 blocking antibodies (10 g/mL) or corresponding isotypic IgG (10 g/mL), and stimulated or not by anti-CD3/CD28 antibodies-coated beads. Non-parametric Wilcoxon paired test was used to compare results obtained in these last 2 conditions. T-cell proliferation was measured among viable cells by flow cytometry. Red squares represent results in CLP mice and white circles in Sham animals. Geometric means with standard deviations (SD) and individual values are shown. Unless otherwise stated, two-sided MannWhitney tests were performed, and only significant p values < 0.05 are shown.

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