Adaptors 10.1 and 10.2 suppress IL-10-induced pSTAT3 and promote IL-2 like pSTAT5 signaling. Dose-response curves for pSTAT5 and pSTAT3 are shown in human CD4 + T cell blasts stimulated with 10 nM IL-10 and increasing concentrations of equimolar Adaptor 10.1 and 10.2. n = 2 replicates per condition. Source data are provided as a Source data file.
