Overview of the study. Gastric glands were sampled from 30 donors. Two hundred seventeen microdissected individual glands from normal, inflamed and/or metaplastic stomach tissue and 21 gastric cancer gland microdissections were whole-genome sequenced, and a further 829 microdissections, each comprising several adjacent glands, were subjected to deep targeted gene sequencing (seq.). Credit: stomach outline in a adapted from Servier Medical Art (https://smart.servier.com/) under a CC BY 4.0 International licence. Outline of laser capture microdissection in a adapted from ref. 8, Springer Nature Limited. M, male; F, female.
