Phylogenetic trees of Ighv sequences from the GCs in a . For each GC, the parental cell fraction and estimated counts of identical cells (±95% confidence interval (CI)), extrapolated to a 2,000-cell GC (in square brackets), are provided. Outgroup cells in GC iii are excluded from calculations. See additional trees in Extended Data Fig. 1b,c . nt, nucleotide; UCA, unmutated common ancestor.