Protein Structure from Scientific Research

A comparison of UM171 (yellow and blue sticks), the side chain of Tyr312 of KBTBD4-TTYML-B (cyan and red sticks) and the side chain of Arg312 of KBTBD4-PR-B (green and blue sticks) at the active site pocket of HDAC1 (pink). The three complex structures are superimposed through HDAC1. Two phenylalanine residues outlining the entrance of the HDAC1 active site tunnel are shown in sticks.

DOI