Venn diagrams depicting the overlaps between genes up- (left) and down- (right) regulated in RIF1-deficient B cells at the indicated times post-activation and the corresponding up-and down-regulated (over nave B cells) categories in the activated (Act) B cell, PB, and PC transcriptional signatures (Minnich et al. 2016). Significance in panels b and c was calculated using a two-sided Wald test, with correction for multiple testing applied through the Benjamini-Hochberg procedure. Source data are provided as a Source Data file. Created in BioRender. Di virgilio, M. (2025) BioRender.com/o81f217.
