Heatmap of NCSC gene sets variation analysis (GVSA) score from patient samples ranked by the ALDH1A3 level. Melanoma patient samples from The Cancer Genome Atlas (TCGA), Lund, and Bergen cohorts unanimously showed positive correlation between ALDH1A3 and NCSC gene sets as annotated.∗p< 0.05,∗∗∗∗p< 0.0001, Spearman’s rank correlation critical probability exact (p) value.