Scatter Plot from Scientific Research

A scatterplot depicting the frequency of high-level copy-number gene AMP versus the ratio of cases with AMP to cases with DEL for 255 GPCRs based on 10,845 cases from TCGA pan-cancer atlas. AMP and DEL refer to gene-level copy numbers 2 and -2, respectively, defined by the GISTIC2 (Genomic Identification of Significant Targets in Cancer version 2) threshold. GPCR genes amplified in >2% of cases, with a ratio of AMP to DEL >10, are labeled in blue. Frequently amplified P2RY genes are labeled in red.

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