Graphs depicting the percentage of IgM+ and IgG1+ cells in the CD138+ populations at the indicated timepoints of the iGB cell culture. n = six Cd19 Cre/+ mice for IgM, five Rif1 F/F Cd19 Cre/+ for IgM, five Cd19 Cre/+ for IgG1, and four Rif1 F/F Cd19 Cre/+ for IgG1 in three independent experiments. Significance in panels ( a , b , c , e , f , g ) was calculated with a two-sided MannWhitney U test, with data presented as mean values SD in panels ( a , c , e , f , and g ), and SEM in panel ( b ). Only significant differences were indicated in panel ( b ). ns: not significant. Source data are provided as a Source Data file. Created in BioRender. Di virgilio, M. (2025) BioRender.com/f53q006.
