Volcano plot of metabolites colored by class. The y axis shows the decadic logarithm of the false discovery rate (FDR)-corrected p value. The dashed line is set at an FDR-corrected p value of 0.05. Metabolites with a negative fold-change value decreased in mice engrafted with C. albicans compared with germ-free mice, while metabolites with a positive fold-change value increased.