Protein Structure from Scientific Research

Cryo-EM density (gray mesh, EMD-30473-2) and structure of the published Integrator complex (PDB:7CUN), consisting of INTS1-2-5-6-7-8-PP2A (Integrator core, gray) and INTS4-9-11 (cleavage module, royal, dark, and light blue). The INTS5 N terminus is colored red. Red and yellow stars mark INTS11s and PP2Acs active sites, respectively. Unmodeled map sections are highlighted by a black outline.

DOI