TNF- and IFN- release kinetics in the control T cell, CAR-T cell, and CAR-T cell + dasatinib conditions with three different treatment schemes: CR regulation (left), prevention (middle), and delay (right). Cytokines were measured from the tumor-on-chip effluents. Data are shown as the mean SEM. The dashed line indicates the lower limit of detection. Data points from day 8 are excluded as the values are mostly below the detection limit.n= 4 chips per condition.
