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Relative abundance of the indicated purine metabolites in WT andUQCRC2−/−H460 cells (n= 3). Unpaired, two-sided t tests were used for the statistical analyses.∗∗∗∗p< 0.0001;∗∗∗p< 0.001,∗∗p< 0.01,∗p< 0.05; n.s.:p> 0.05. Error bars denote SEM. BioRender was used to generate the illustration.

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