Line Step from Scientific Research

Schematics (left) and diabetes incidence (right) of NOD.Rag1−/− recipients post transfer of splenocytes from age- and sex-matched NOD or NOD.Cxcl16−/− donors. Data are mean ± SEM. Each dot represents individual mice (D, F, G, I, and J), islets (K), or experiments (B and C). The results are from at least 2–4 independent experiments. Statistics are analyzed by Mann-Whitney test (B, F, G, J, and K), paired t test (C), one-way ANOVA with Dunnett’s multiple comparisons test (D and I), or log-rank (Mantel-Cox) test.∗p< 0.05;∗∗p< 0.01;∗∗∗p< 0.001;∗∗∗∗p< 0.0001. See alsoFigure S3.

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