Line Plot from Scientific Research

The effects of diffusion are visible using contact data. Here, the initial chromatin conformation is modeled as a 3D random walk. Without diffusion (purple), random walks yield a power law relating distance along the polymer chain, measured in monomers,s, to the probability that two monomers are in contact,p(s). Diffusion erases the power law up to the scale of the RMSD (lower: green; higher: red). Theoretical calculations (dashed) match simulations (solid). As particles diffuse, they again erase the initial conformation at increasingly large scales.

DOI