PaleoHi-C data (yellow) and aDNA-Seq data (purple) for the same sample were aligned to African elephant. The log-log histogram shows relative contact probability vs. 1D genomic distance between read ends. A fraction of PaleoHi-C reads reflects contacts between loci that lie far away in 1D. Not so for aDNA-Seq. For the (E) inset, similar plot comparing PaleoHi-C on woolly mammoth skin vs. in situ Hi-C on Asian elephant skin. Power laws are seen in the 1-10 Mb distance range (solid lines), with nearly identical scalings (mammoth: -0.96; elephant: -0.98).
