Forest Plot from Scientific Research

Impact of mitochondrial-related PTVs on the risks of end-stage liver diseases and liver-related mortality. The impact of PTVs on the risk of end-stage liver diseases (fibrosis and cirrhosis of liver and liver cancer) and liver disease-related mortality was evaluated using a COX regression model. The model was adjusted for age, sex, alcohol intake frequency, ever smoked, physical activity level, education deprivation score, household income, BMI, hypertension, diabetes, and dyslipidemia. The incidence rates (per 100,000 person-years, /10^5pys) of diseases were also calculated in the whole population and subgroups. Abbreviations: PTV, protein truncating variant; HR, hazard ratio; CI, confidence interval

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