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Summary of the direct effects, indirect effects, and mediation effects of ferritin in the association of fasting insulin and steatosis, and of liver iron in the association of ferritin and steatosis (meta-analysis). FI, fasting insulin; HbA1c, hemoglobin A1c; MVMR, multivariable Mendelian randomization; IVW, inverse-variance weighting; OR, odds ratio; 95% CI, 95% confidence interval. * P value < 0.05, ** P value < 0.01, *** P value < 0.001

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