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Schematic of the Doxycycline (DOX)-inducible lentiviral shRNA expression constructs used. Tet-regulated vectors expressing GFP-coupled miRE shRNAs and rtTA as a Tet-On all-in-one construct. Lentiviral transduction and supplementation with DOX leads to expression of GFP as well as the expression of the individual shRNA-cassette.
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