Line Plot from Scientific Research

Competition assays of MFRN1 high- and low-expressing cell lines. SpCas9 competent cell lines expressing either a non-targeting sgRNA (sgCTR) or a sgRNA targeting MFRN1 (sgMFRN1) were mixed with cells transduced with a lentiviral construct expressing either a non-targeting sgRNA (sgCTR) or a sgRNA targeting MFRN2 (sgMFRN2) together with GFP in a 30:70 ratio and followed by FACS over 12 days with measurement at indicated time points. Results are shown as the mean SD of the ratio of GFP + cells compared to t0 for each assay. n = 3 for biological replicates.

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