Volcano Plot from Scientific Research

Genetic vulnerabilities in chr8p deleted (DEL) versus ch8p non-deleted (non-DEL) cell lines. The vulnerabilities represent the differential cell fitness effects (CERES scores) and are tested for significance using Wilcoxon’s rank-sum test with ISW multiple hypothesis correction (see methods). Significant vulnerabilities (chr8p synthetic lethalities; 8pSL) are defined at an FDR of 25% and a dCERES score < - 0.075.

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