Illustration from Scientific Research

LPA gene structure: each kringle domain (KIV-1 to KIV-10 and KV) consists of two exons and the protease domain of 6 exons. In both reference genome assemblies hg19 and hg38, the KIV-2 VNTR (green) is represented with 6 KIV-2 repeats, one being a KIV-2B. In 10,927 Central-European individuals from [ 13 ], the average, minimum, and maximum number of KIV-2 units measured at the protein level in plasma using Western Blot were 20, 2, and 36 KIV-2, respectively.

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