Enrichment and depletion in each indicated comparison of species-specific and shared oCGIs ( top: A-only, B-only, Shared) and species-specific and shared peaks ( left : A-only, B-only, Shared), compared to a null expectation of no association between oCGI turnover and peak turnover. Results are shown as in Fig. 3 C,D, with enrichment in green for H3K27ac and yellow for H3K4me2, and depletion in gray. One representative comparison is shown for developing cortex (8.5 post-conception weeks (p.c.w.) in human versus embryonic day 14.5 in mouse) and developing limb (embryonic day 41 in human versus embryonic day 12.5 in mouse).