Protein Structure from Scientific Research

Proposed binding modes for PG in mutant Y137F. Carbon atoms of PG are shown in orange. The binding area of the catalytic site is represented as a transparent grey surface. Carbon atoms of SAM cofactor are shown in green. TheecCFAS is shown as thin ribbon. H-bonds are shown as red dots, whereas hydrophobic interactions are represented as green dots. The mutated residue is coloured and labelled in red. Blue shadow areas on the 2D molecule-enzyme interactions diagram represent solvent exposure areas.

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