Line Plot from Scientific Research

D67R1 and M47R1 PELDOR distance distributions under different CD conditions. D67R1 and M47R1 top five PELDOR data distributions and bottom four distributions showing the modeled distances for the closed (“C”, dark red), sub-conducting (“S”, green), fully open (“FO”, cyan), and desensitized (“DS”, gold) states with respective colored dash lines indicating the most probable distances based on ourin silicomodeling. CD-to-lipid ratios and incubation times used are: a) 12:1, 16 h, b) 6:1, 16 h, c) 2:1, 16 h, d) 2:1, 4 h, and e) initial state (control, no CD). Experimental traces (zoom) and modeled traces scaled with experimental modulation depth from control for different percentages of MscS sub-conducting state (PDB:6VYL) populations within the ensemble for D67R1 (G column) and M47

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