Protein Structure from Scientific Research

Structural overview of HLA-DR1 presenting WT HA320-335peptide. The HLA-II groove is shown as cartoon representation (gray), and peptide is shown as sticks (C atoms = yellow, N = blue, O = red). Peptide residues are labeled according to the peptide register, i.e., Tyr1 inP1. Inset boxes show a focused view of the C-PFR with inset labeled electron density maps as a mesh representation: 2mFo-DFc maps contoured at 1.0 (top) and 0.5 σ (middle) and mFo-DFc omit map, which was calculated in the absence of peptide atoms (bottom; −3.0 σ = red, +3.0 σ = green).

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