Heatmap from Scientific Research

Heatmap of relative transcriptomic levels at the pluripotent stem cell stage (day 0) and through directed differentiation (day 6 and day 12, NSC stage) into neurons (day 27 and day 42), from left to right. Top: genes implicated in pluripotency and various stages of human corticogenesis. Bottom: genes and pathways involved in proteostasis (ER stress/UPR). x axis: healthy, heterozygous control in blue (CTRL-33-xx) and XP patients with neurodegeneration in red (NXPx-xx-xx). Three replicates were available for each genotype (R1, R2, and R3).

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