Graphic illustration elucidating the progression from diabody to scDb, culminating in IgG-like scDb-Fc. Tabulation of pseudovirus neutralization metrics for an array of diabodies and their constructs against specific Omicron variants is provided. In the figure, the yellow highlight indicates a pronounced synergistic effect when juxtaposed with IgG or cocktail formulations. Molecular weight variations were considered, with results delineated in consistent nM units. Each neutralization experiment was performed three times with two replicates (n= 2). IC50values represent the mean data from three independent experiments. See also Figure S5.
