Avoidance of open arms in ArchT and tdTomato control mice in each condition of the PV interneuron inhibition protocol. ArchT mice significantly decreased their time exploring the open arms after the PV interneuron manipulation and 24 h later in a follow-up test (without light manipulation) compared to the tdTomato controls. Two-way repeated ANOVA,F(2,28)= 3.4, andp= 0.047 for factor virus type including day 1 conditions with post-hoc multiple comparisons (Tukey)p= 0.0136 for light off, ArchT miceN= 8 and tdTomato miceN= 8. For the follow-up with ArchT miceN= 7 and tdTomato miceN= 5, a two-tailed Mann-Whitney U test was independently applied withp= 0.0303. Error bars represent +- SEM.