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Workflow to assess endogenous frequency mixing in cell membrane potential. For a given trace of endogenous membrane potential, the instantaneous phases of four frequency mixing components (roots:f1,f2>f1, products:Δf=f2−f1,∑f=f1+f2) are extracted. Each subset of three phases (triplet) are used to construct a test matrix, which, when compared to a null distribution, defines the joint higher-order interaction (JHOI) strength heuristic.
#Illustration#Line Plot#Heatmap#Histogram#Cell Membrane Potential#Frequency Mixing#Endogenous Membrane Potential#Instantaneous Phase#Frequency Component#Test Matrix#Null Distribution#Joint Higher-Order Interaction (JHOI)
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