Scatter Plot from Scientific Research

Screening for serum IgG antibodies binding to the EDIII of POWV (lineage II, A) in ELISA. Each dot represents the IgG reactivity of an individual participant at 1:500 serum dilution (single well). Samples with optical density above 0.6 (dotted lines) were selected for the neutralization screening in (C) and (D). In (A)–(D): black, dark gray, and light gray represent samples from New York, Brazil, and Mexico, respectively. In red is MEX58 and in blue a sample from a TBEV-vaccinated individual. The p-values in (A)–(D) were determined with the Mann-Whitney test.

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