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Transcript levels were determined by qPCR for MutS and LIG1 (D), and MutL (E) normalized to un-transfected/transduced controls. Data compared by ANOVA with Bonferroni’s post hoc. Error bars show SEM.N= 3, error bars ±SEM,*=p< 0.05. Two guides per target were taken forward, highlighted by green dashed boxes.
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