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Kv4.1 wild-type channels (WT, gray quadrants) and variant channels with amino acid substitutions (quadrants with red dots) were functionally analyzed in a ternary configuration, i.e., with both KChIP (orange) and DPP (blue, see alsoFigure S1andVideo S1) in Xenopus laevis oocytes (seematerial and methods).
#Illustration#Chemical Structure#Kv4.1 Wild-Type Channels#Variant Channels#Amino Acid Substitutions#KChIP#DPP#Xenopus Laevis Oocytes
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