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Open access visualization of Illustration, Mechanostimulation, Calcium Release, ER, TRPV1
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Illustration scheme for mechanostimulation-induced Ca2+release from ER via TRPV1 and PKD2 channels. 200-ms pulses of 240 mW/cm2blue light at 2-s intervals were delivered to the whole cell. Scale bars, 10 μm. Circles indicate measurements of individual cells. Traces and bars represent mean ± SEM. n > 70 from ≥3 independent experiments. The number of experiments, statistical tests, and exact p values are provided inTable S1(N.S. p > 0.05,∗p < 0.05,∗∗p < 0.01,∗∗∗∗p < 0.0001). See alsoFigures S3,S4, andS6andVideo S5.

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